3MH9

Crystal structure of LprG mutant V91W from Mycobacterium tuberculosis

Summary for 3MH9

• Entry DOI: 10.2210/pdb3mh9/pdb
• Related: 3MH8 3MHA
• Descriptor: Lipoprotein lprG (2 entities in total)
• Functional Keywords: lipoprotein, mutant lprg, glycolipid binding protein, lipid binding protein, structural genomics, tb structural genomics consortium, tbsgc
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cell membrane; Lipid-anchor: P0A5I8
• Total number of polymer chains: 2
• Total formula weight: 45985.38

Authors

Tsai, H.-C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2010-04-07, release date: 2010-09-01, Last modification date: 2024-04-03)

• Primary citation: Drage, M.G.,Tsai, H.C.,Pecora, N.D.,Cheng, T.Y.,Arida, A.R.,Shukla, S.,Rojas, R.E.,Seshadri, C.,Moody, D.B.,Boom, W.H.,Sacchettini, J.C.,Harding, C.V.; Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2.; Nat.Struct.Mol.Biol., 17:1088-1095, 2010; PubMed: 20694006; DOI: 10.1038/nsmb.1869

Experimental method

X-RAY DIFFRACTION (1.794 Å)