3MCO

Crystal Structure of the 6-hyroxymethyl-7,8-dihydropterin pyrophosphokinase dihydropteroate synthase bifunctional enzyme from Francisella tularensis

3MCO の概要

• エントリーDOI: 10.2210/pdb3mco/pdb
• 関連するPDBエントリー: 3MCM 3MCN
• 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase, 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (5 entities in total)
• 機能のキーワード: folate, tim barrel, kinase, synthase, hppk, dhps, pterin, transferase
• 由来する生物種: Francisella tularensis subsp. holarctica
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 103062.86

構造登録者

Pemble IV, C.W.,Mehta, P.K.,Mehra, S.,Li, Z.,Lee, R.E.,White, S.W. (登録日: 2010-03-29, 公開日: 2010-12-22, 最終更新日: 2023-09-06)

• 主引用文献: Pemble, C.W.,Mehta, P.K.,Mehra, S.,Li, Z.,Nourse, A.,Lee, R.E.,White, S.W.; Crystal structure of the 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.dihydropteroate synthase bifunctional enzyme from Francisella tularensis.; Plos One, 5:e14165-e14165, 2010; PubMed: 21152407; DOI: 10.1371/journal.pone.0014165

実験手法

X-RAY DIFFRACTION (2.3 Å)