3MBZ

OXA-24 beta-lactamase complex soaked with 10mM SA4-17 inhibitor for 15min

Summary for 3MBZ

Entry DOI	10.2210/pdb3mbz/pdb
Related	3FV7 3FYZ 3FZC 3G4P
Descriptor	Betalactamase OXA24, SULFATE ION, (2S,3R)-2-[(7-aminocarbonyl-2-methanoyl-indolizin-3-yl)amino]-4-aminocarbonyloxy-3-methyl-3-sulfino-butanoic acid, ... (4 entities in total)
Functional Keywords	beta-lactamase, beta-lactamase inhibitor, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Acinetobacter baumannii
Total number of polymer chains	1
Total formula weight	28109.12
Authors	Sampson, J.,van den Akker, F. (deposition date: 2010-03-26, release date: 2011-03-16, Last modification date: 2011-07-13)
Primary citation	Bou, G.,Santillana, E.,Sheri, A.,Beceiro, A.,Sampson, J.M.,Kalp, M.,Bethel, C.R.,Distler, A.M.,Drawz, S.M.,Pagadala, S.R.,van den Akker, F.,Bonomo, R.A.,Romero, A.,Buynak, J.D. Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase J.Am.Chem.Soc., 132:13320-13331, 2010 Cited by PubMed: 20822105 DOI: 10.1021/ja104092z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation