3MB6
Human CK2 catalytic domain in complex with a difurane derivative inhibitor (CPA)
Summary for 3MB6
Entry DOI | 10.2210/pdb3mb6/pdb |
Related | 3MB7 |
Descriptor | Casein kinase II subunit alpha, naphtho[2,1-b:7,6-b']difuran-2,8-dicarboxylic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | kinases, difurane, inhibitor, ck2, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 40042.52 |
Authors | Reiser, J.-B.,Prudent, R.,Claude, C. (deposition date: 2010-03-25, release date: 2010-05-05, Last modification date: 2023-09-06) |
Primary citation | Lopez-Ramos, M.,Prudent, R.,Moucadel, V.,Sautel, C.F.,Barette, C.,Lafanechere, L.,Mouawad, L.,Grierson, D.,Schmidt, F.,Florent, J.C.,Filippakopoulos, P.,Bullock, A.N.,Knapp, S.,Reiser, J.B.,Cochet, C. New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights. Faseb J., 24:3171-3185, 2010 Cited by PubMed: 20400536DOI: 10.1096/fj.09-143743 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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