3MB3

Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP)

3MB3 の概要

• エントリーDOI: 10.2210/pdb3mb3/pdb
• 関連するPDBエントリー: 3MB4
• 分子名称: PH-interacting protein, 1-methylpyrrolidin-2-one (3 entities in total)
• 機能のキーワード: phip, pleckstrin homology domain interacting protein, dcaf14, ndrp, ddb1 and cul4 associated factor 14, sgc, structural genomics consortium, bromodomain, phosphoprotein, wd repeat, signaling protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus (By similarity): Q8WWQ0
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16230.39

構造登録者

Filippakopoulos, P.,Picaud, S.,Keates, T.,Ugochukwu, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2010-03-25, 公開日: 2010-04-14, 最終更新日: 2023-09-06)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S.; Histone recognition and large-scale structural analysis of the human bromodomain family.; Cell(Cambridge,Mass.), 149:214-231, 2012; PubMed: 22464331; DOI: 10.1016/j.cell.2012.02.013

実験手法

X-RAY DIFFRACTION (2.25 Å)