3MAZ

Crystal Structure of the Human BRDG1/STAP-1 SH2 Domain in Complex with the NTAL pTyr136 Peptide

3MAZ の概要

• エントリーDOI: 10.2210/pdb3maz/pdb
• 分子名称: Signal-transducing adaptor protein 1, CheD family protein, MALONATE ION, ... (4 entities in total)
• 機能のキーワード: modular domain, phosphotyrosine, specificity, cytoplasm, phosphoprotein, sh2 domain, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm (Potential): Q9ULZ2; Cell membrane; Single-pass type III membrane protein: Q9GZY6
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 15582.51

構造登録者

Kaneko, T.,Huang, H.,Zhao, B.,Li, L.,Liu, H.,Voss, C.K.,Wu, C.,Schiller, M.R.,Li, S.S. (登録日: 2010-03-24, 公開日: 2010-05-12, 最終更新日: 2023-11-22)

• 主引用文献: Kaneko, T.,Huang, H.,Zhao, B.,Li, L.,Liu, H.,Voss, C.K.,Wu, C.,Schiller, M.R.,Li, S.S.; Loops govern SH2 domain specificity by controlling access to binding pockets.; Sci.Signal., 3:ra34-ra34, 2010; PubMed: 20442417; DOI: 10.1126/scisignal.2000796

実験手法

X-RAY DIFFRACTION (1.9 Å)