3M9F

HIV protease complexed with compound 10b

Summary for 3M9F

Entry DOI	10.2210/pdb3m9f/pdb
Descriptor	HIV-1 protease, N-[(1S,5S)-5-{[(4-aminophenyl)sulfonyl](3-methylbutyl)amino}-1-methyl-6-oxohexyl]-Nalpha-(methoxycarbonyl)-beta-phenyl-L-phenylalaninamide, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	hiv, protease, transferase
Biological source	Human immunodeficiency virus 1
Total number of polymer chains	2
Total formula weight	23069.58
Authors	Su, H.P. (deposition date: 2010-03-22, release date: 2010-06-30, Last modification date: 2024-02-21)
Primary citation	Jones, K.L.,Holloway, M.K.,Su, H.P.,Carroll, S.S.,Burlein, C.,Touch, S.,DiStefano, D.J.,Sanchez, R.I.,Williams, T.M.,Vacca, J.P.,Coburn, C.A. Epsilon substituted lysinol derivatives as HIV-1 protease inhibitors. Bioorg.Med.Chem.Lett., 20:4065-4068, 2010 Cited by PubMed: 20547452 DOI: 10.1016/j.bmcl.2010.05.082 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation