3M3E
Crystal Structure of Agrocybe aegerita lectin AAL mutant E66A complexed with p-Nitrophenyl Thomsen-Friedenreich disaccharide
Summary for 3M3E
Entry DOI | 10.2210/pdb3m3e/pdb |
Related | 3AFK 3M3C 3M3O 3M3Q |
Related PRD ID | PRD_900084 |
Descriptor | Anti-tumor lectin, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, P-NITROPHENOL, ... (4 entities in total) |
Functional Keywords | galectin, aal, mutant, thomsen-friedenreich disaccharide, apoptosis, hydrolase, lectin, nuclease, gal-beta-1, 3-galnac-alpha-o-p-nitrophenyl |
Biological source | Agrocybe aegerita (Black poplar mushroom) |
Total number of polymer chains | 4 |
Total formula weight | 71262.77 |
Authors | |
Primary citation | Feng, L.,Sun, H.,Zhang, Y.,Li, D.F.,Wang, D.C. Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen Faseb J., 24:3861-3868, 2010 Cited by PubMed: 20530247DOI: 10.1096/fj.10-159111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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