3M1S

Structure of Ruthenium Half-Sandwich Complex Bound to Glycogen Synthase Kinase 3

Summary for 3M1S

Entry DOI	10.2210/pdb3m1s/pdb
Descriptor	Glycogen synthase kinase-3 beta, Ruthenium pyridocarbazole (3 entities in total)
Functional Keywords	transferase, enzyme inhibitor, organometallic compound, ruthenium center, ruthenium pyridocarbazole, atp-binding, kinase, phosphoprotein, serine/threonine-protein kinase, wnt signaling pathway, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P49841
Total number of polymer chains	2
Total formula weight	94595.30
Authors	Atilla-Gokcumen, G.E.,Di Costanzo, L.,Zimmermann, G.,Meggers, E. (deposition date: 2010-03-05, release date: 2010-12-22, Last modification date: 2023-09-06)
Primary citation	Atilla-Gokcumen, G.E.,Di Costanzo, L.,Meggers, E. Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3beta J.Biol.Inorg.Chem., 16:45-50, 2011 Cited by PubMed: 20821241 DOI: 10.1007/s00775-010-0699-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.134 Å)

Structure validation