Crystal structure of the TRAF1:TRAF2:cIAP2 complex

Summary for 3M0D

Related3M06 3M0A
DescriptorTNF receptor-associated factor 2, TNF receptor-associated factor 1, Baculoviral IAP repeat-containing protein 3, ... (5 entities in total)
Functional Keywordstrimeric helix coiled coiled, acetylation, alternative splicing, apoptosis, coiled coil, cytoplasm, metal-binding, ubl conjugation, polymorphism, chromosomal rearrangement, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q12933
Cytoplasm (Potential) Q13489
Total number of polymer chains4
Total molecular weight31261.3
Kabaleeswaran, V.,Wu, H. (deposition date: 2010-03-02, release date: 2010-04-28, Last modification date: 2011-07-13)
Primary citation
Zheng, C.,Kabaleeswaran, V.,Wang, Y.,Cheng, G.,Wu, H.
Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
Mol.Cell, 38:101-113, 2010
PubMed: 20385093 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2010.03.009
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.272120.4%5.8%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report