3LU8
Human serum albumin in complex with compound 3
Summary for 3LU8
Entry DOI | 10.2210/pdb3lu8/pdb |
Related | 3LU6 3LU7 |
Descriptor | Serum albumin, N-[5-(5-{[(2,4-dimethyl-1,3-thiazol-5-yl)sulfonyl]amino}-6-fluoropyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]acetamide (3 entities in total) |
Functional Keywords | binding sites, ligands, protein binding, serum albumin, hsa, proteros biostructures gmbh, transport protein, astrazeneca, drug design |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02768 |
Total number of polymer chains | 2 |
Total formula weight | 134025.48 |
Authors | Buttar, D.,Colclough, N.,Gerhardt, S.,MacFaul, P.A.,Phillips, S.D.,Plowright, A.,Whittamore, P.,Tam, K.,Maskos, K.,Steinbacher, S.,Steuber, H. (deposition date: 2010-02-17, release date: 2010-10-27, Last modification date: 2011-07-13) |
Primary citation | Buttar, D.,Colclough, N.,Gerhardt, S.,Macfaul, P.A.,Phillips, S.D.,Plowright, A.,Whittamore, P.,Tam, K.,Maskos, K.,Steinbacher, S.,Steuber, H. A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions Bioorg.Med.Chem., 18:7486-7496, 2010 Cited by PubMed: 20869876DOI: 10.1016/j.bmc.2010.08.052 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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