3LTN

Inhibitor-stabilized topoisomerase IV-DNA cleavage complex (S. pneumoniae)

Summary for 3LTN

• Entry DOI: 10.2210/pdb3ltn/pdb
• Related: 2NOV 3FOE 3FOF 3K9F 3KSA 3KSB
• Descriptor: DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, 5'-D(*AP*CP*CP*AP*AP*GP*GP*T*CP*AP*TP*GP*AP*AP*T)-3', ... (9 entities in total)
• Functional Keywords: topoisomerase, protein-dna cleavage complex, streptococcus pneumoniae, dna-binding, quinolone, dione, cleaved form, topoisomerase-dna complex, isomerase-dna complex, isomerase/dna
• Biological source: Streptococcus pneumoniae; More
• Cellular location: Cell membrane; Peripheral membrane protein (By similarity): P72525
• Total number of polymer chains: 8
• Total formula weight: 195339.30

Authors

Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2010-02-16, release date: 2010-05-05, Last modification date: 2023-11-01)

• Primary citation: Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R.; Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases; Plos One, 5:e11338-e11338, 2010; PubMed: 20596531; DOI: 10.1371/journal.pone.0011338

Experimental method

X-RAY DIFFRACTION (3.1 Å)