Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3LT4

Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant PB4

Summary for 3LT4
Entry DOI10.2210/pdb3lt4/pdb
Related1UH5 1V35 1ZSN 1ZXL 2OL4 2OOS 3LSY 3LT0 3LT1 3LT2
DescriptorEnoyl-ACP reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2-(2-amino-4-chlorophenoxy)-5-chlorophenol, ... (4 entities in total)
Functional Keywordstriclosan, triclosan variant, enoyl-acp reductase, oxidoreductase, p.falciparum
Biological sourcePlasmodium falciparum
Total number of polymer chains2
Total formula weight76355.44
Authors
Maity, K.,Bhargav, S.P.,Surolia, N.,Surolia, A.,Suguna, K. (deposition date: 2010-02-15, release date: 2010-06-16, Last modification date: 2023-11-01)
Primary citationMaity, K.,Bhargav, S.P.,Sankaran, B.,Surolia, N.,Surolia, A.,Suguna, K.
X-ray crystallographic analysis of the complexes of enoyl acyl carrier protein reductase of Plasmodium falciparum with triclosan variants to elucidate the importance of different functional groups in enzyme inhibition
Iubmb Life, 62:467-476, 2010
Cited by
PubMed: 20503440
DOI: 10.1002/iub.327
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon