3LQ9
Crystal structure of human REDD1, a hypoxia-induced regulator of mTOR
Summary for 3LQ9
Entry DOI | 10.2210/pdb3lq9/pdb |
Descriptor | DNA-damage-inducible transcript 4 protein (2 entities in total) |
Functional Keywords | redd1 ddit4 mtor, hypoxia, cancer, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion : Q9NX09 |
Total number of polymer chains | 2 |
Total formula weight | 29661.80 |
Authors | Vega-Rubin-de-Celis, S.,Abdallah, Z.,Brugarolas, J.,Zhang, X. (deposition date: 2010-02-08, release date: 2010-03-09, Last modification date: 2017-11-01) |
Primary citation | Vega-Rubin-de-Celis, S.,Abdallah, Z.,Kinch, L.,Grishin, N.V.,Brugarolas, J.,Zhang, X. Structural analysis and functional implications of the negative mTORC1 regulator REDD1. Biochemistry, 49:2491-2501, 2010 Cited by PubMed: 20166753DOI: 10.1021/bi902135e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report