3LPQ

Human MitoNEET with 2Fe-2S Coordinating Ligand His 87 Replaced With Cys

3LPQ の概要

• エントリーDOI: 10.2210/pdb3lpq/pdb
• 分子名称: CDGSH iron sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER (3 entities in total)
• 機能のキーワード: cdgsh protein fold, 2fe-2s cluster, neet fold, homodimer, iron, iron-sulfur, membrane, metal-binding, mitochondrion, mitochondrion outer membrane, signal-anchor, transmembrane, metal binding protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion outer membrane; Single-pass type III membrane protein: Q9NZ45
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18803.02

構造登録者

Conlan, A.R.,Homer, C.,Axelrod, H.L.,Cohen, A.E.,Abresch, E.C.,Zuris, J.,Nechushtai, R.,Paddock, M.L.,Jennings, P.A. (登録日: 2010-02-05, 公開日: 2011-06-01, 最終更新日: 2024-02-21)

• 主引用文献: Conlan, A.R.,Paddock, M.L.,Homer, C.,Axelrod, H.L.,Cohen, A.E.,Abresch, E.C.,Zuris, J.A.,Nechushtai, R.,Jennings, P.A.; Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment.; Acta Crystallogr.,Sect.D, 67:516-523, 2011; PubMed: 21636891; DOI: 10.1107/S0907444911011577

実験手法

X-RAY DIFFRACTION (1.7 Å)