3LPN

Crystal structure of the phosphoribosylpyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with an ATP analog (AMPCPP).

3LPN の概要

• エントリーDOI: 10.2210/pdb3lpn/pdb
• 関連するPDBエントリー: 1IBS 1U9Y 1U9Z 2H06 2HCR
• 分子名称: Ribose-phosphate pyrophosphokinase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: phosphoribosyltransferase, atp analog binding, atp-binding, kinase, metal-binding, nucleotide biosynthesis, nucleotide-binding, transferase
• 由来する生物種: Thermoplasma volcanium
• 細胞内の位置: Cytoplasm : Q97CA5
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65933.61

構造登録者

Cherney, M.M.,Cherney, L.T.,Garen, C.R.,James, M.N.G. (登録日: 2010-02-05, 公開日: 2011-02-09, 最終更新日: 2023-09-06)

• 主引用文献: Cherney, M.M.,Cherney, L.T.,Garen, C.R.,James, M.N.; The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs.; J.Mol.Biol., 413:844-856, 2011; PubMed: 21963988; DOI: 10.1016/j.jmb.2011.09.007

実験手法

X-RAY DIFFRACTION (1.8 Å)