3LPL

E. coli pyruvate dehydrogenase complex E1 component E571A mutant

3LPL の概要

• エントリーDOI: 10.2210/pdb3lpl/pdb
• 関連するPDBエントリー: 2IEA 3LQ2 3LQ4
• 分子名称: Pyruvate dehydrogenase E1 component, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, THIAMINE DIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: thdp, pyruvate dehydrogenase, oxidoreductase, glycolysis, metal-binding, pyruvate, thiamine pyrophosphate
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 200764.04

構造登録者

Furey, W. (登録日: 2010-02-05, 公開日: 2010-03-02, 最終更新日: 2023-09-06)

• 主引用文献: Nemeria, N.S.,Arjunan, P.,Chandrasekhar, K.,Mossad, M.,Tittmann, K.,Furey, W.,Jordan, F.; Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a "direct pathway" between the 4'-aminopyrimidine N1' atoms.; J.Biol.Chem., 285:11197-11209, 2010; PubMed: 20106967; DOI: 10.1074/jbc.M109.069179

実験手法

X-RAY DIFFRACTION (2.1 Å)