Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE EPE A 889 |
| Chain | Residue |
| A | VAL65 |
| B | GLN790 |
| B | VAL791 |
| B | HOH1022 |
| A | GLU66 |
| A | GLU67 |
| A | GLN68 |
| A | PRO69 |
| A | GLU70 |
| A | LYS367 |
| A | HOH1144 |
| B | TYR787 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE TPP A 887 |
| Chain | Residue |
| A | SER109 |
| A | GLN140 |
| A | HIS142 |
| A | GLY229 |
| A | ASP230 |
| A | GLY231 |
| A | GLU232 |
| A | ASN260 |
| A | GLN262 |
| A | ARG263 |
| A | LEU264 |
| A | MG888 |
| B | ILE569 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 888 |
| Chain | Residue |
| A | GLY229 |
| A | ASP230 |
| A | ASN258 |
| A | ASN260 |
| A | GLN262 |
| A | TPP887 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 890 |
| Chain | Residue |
| A | ARG79 |
| A | ARG82 |
| A | ARG86 |
| A | TYR394 |
| A | HOH1206 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE TPP B 887 |
| Chain | Residue |
| A | ILE569 |
| B | SER109 |
| B | GLN140 |
| B | HIS142 |
| B | MET194 |
| B | GLY229 |
| B | ASP230 |
| B | GLY231 |
| B | GLU232 |
| B | ASN258 |
| B | ASN260 |
| B | GLN262 |
| B | LYS392 |
| B | MG888 |
| B | HOH1096 |
| B | HOH1151 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 888 |
| Chain | Residue |
| B | ASP230 |
| B | ASN260 |
| B | GLN262 |
| B | TPP887 |
| B | HOH1151 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EPE B 889 |
| Chain | Residue |
| B | VAL65 |
| B | GLU66 |
| B | GLN68 |
| B | LYS367 |
| B | HOH1201 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 890 |
| Chain | Residue |
| B | ARG79 |
| B | ARG82 |
| B | ARG86 |
| B | TYR394 |
| B | PHE424 |
| B | HOH1026 |
| B | HOH1128 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP230 | |
| A | ASN260 | |
| B | ASN260 | |
| B | GLN262 | |
| A | GLN262 | |
| B | ASP230 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS715 | |
| B | LYS715 | |
