3LPH

Crystal structure of the HIV-1 Rev dimer

Summary for 3LPH

Entry DOI	10.2210/pdb3lph/pdb
Descriptor	Protein Rev, SULFATE ION, BROMIDE ION, ... (5 entities in total)
Functional Keywords	helix-loop-helix, rna-binding arginine rich motif, protein oligomerization, aids, host cytoplasm, host nucleus, host-virus interaction, mrna transport, phosphoprotein, rna-binding, transport, viral protein
Biological source	Human immunodeficiency virus type 1 (HIV-1)
Cellular location	Host nucleus, host nucleolus : P69718
Total number of polymer chains	4
Total formula weight	35188.79
Authors	Daugherty, M.D. (deposition date: 2010-02-05, release date: 2010-12-08, Last modification date: 2024-04-03)
Primary citation	Daugherty, M.D.,Liu, B.,Frankel, A.D. Structural basis for cooperative RNA binding and export complex assembly by HIV Rev. Nat.Struct.Mol.Biol., 17:1337-1342, 2010 Cited by PubMed: 20953181 DOI: 10.1038/nsmb.1902 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation