3LNY
Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide
Summary for 3LNY
Entry DOI | 10.2210/pdb3lny/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 13, Rap guanine nucleotide exchange factor 6, THIOCYANATE ION, ... (5 entities in total) |
Functional Keywords | pdz2, structural genomics, protein structure initiative, psi-2, center for eukaryotic structural genomics, cesg, cytoskeleton, cell membrane, guanine-nucleotide releasing factor, signaling protein-signaling protein complex, signaling protein/signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton : Q12923 Cytoplasm : Q8TEU7 |
Total number of polymer chains | 2 |
Total formula weight | 10902.14 |
Authors | Zhang, J.,Chang, A.,Ke, H.,Phillips Jr., G.N.,Lee, A.L.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2010-02-03, release date: 2010-03-23, Last modification date: 2024-02-21) |
Primary citation | Zhang, J.,Sapienza, P.J.,Ke, H.,Chang, A.,Hengel, S.R.,Wang, H.,Phillips, G.N.,Lee, A.L. Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E. Biochemistry, 49:9280-9291, 2010 Cited by PubMed: 20839809DOI: 10.1021/bi101131f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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