3LLR

Crystal structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 alpha

3LLR の概要

• エントリーDOI: 10.2210/pdb3llr/pdb
• 分子名称: DNA (cytosine-5)-methyltransferase 3A, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: transferase, dna methyltransferase, methylysine binding, structural genomics consortium, sgc, alternative promoter usage, chromatin regulator, dna-binding, metal-binding, methyltransferase, nucleus, phosphoprotein, repressor, s-adenosyl-l-methionine, zinc-finger
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus : Q9Y6K1
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 87444.76

構造登録者

Qiu, W.,Dombrovski, L.,Ni, S.,Weigelt, J.,Boutra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (登録日: 2010-01-29, 公開日: 2010-03-23, 最終更新日: 2023-09-06)

• 主引用文献: Wu, H.,Zeng, H.,Lam, R.,Tempel, W.,Amaya, M.F.,Xu, C.,Dombrovski, L.,Qiu, W.,Wang, Y.,Min, J.; Structural and histone binding ability characterizations of human PWWP domains.; Plos One, 6:e18919-e18919, 2011; PubMed: 21720545; DOI: 10.1371/journal.pone.0018919

実験手法

X-RAY DIFFRACTION (2.3 Å)