3LL2
Monomeric Griffithsin in Complex with a High-Mannose Branched Carbohydrate
3LL2 の概要
エントリーDOI | 10.2210/pdb3ll2/pdb |
関連するPDBエントリー | 2gty 2guc 2gud 2gue 2gux 2hyq 2hyr 2nu5 2nuo 3LKY 3LL0 3LL1 |
分子名称 | Griffithsin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, 1,2-ETHANEDIOL, ... (5 entities in total) |
機能のキーワード | lectin, sugar-binding, anti-hiv, high mannose, man9, gp120, gp41, jacalin-related, mannose-binding, sugar binding protein |
由来する生物種 | Griffithsia (Red alga) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 14674.59 |
構造登録者 | |
主引用文献 | Moulaei, T.,Shenoy, S.R.,Giomarelli, B.,Thomas, C.,McMahon, J.B.,Dauter, Z.,O'Keefe, B.R.,Wlodawer, A. Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity. Structure, 18:1104-1115, 2010 Cited by PubMed: 20826337DOI: 10.1016/j.str.2010.05.016 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (0.97 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード