3LH5

Crystal Structure of the SH3-Guanylate kinase core domain of ZO-1

3LH5 の概要

• エントリーDOI: 10.2210/pdb3lh5/pdb
• 分子名称: Tight junction protein ZO-1 (2 entities in total)
• 機能のキーワード: zo-1, sh3-guanylate kinase, intramolecular fold, cell junction, cell membrane, membrane, phosphoprotein, sh3 domain, tight junction, protein binding
• 由来する生物種: Homo sapiens; 詳細
• 細胞内の位置: Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q07157
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29047.04

構造登録者

Lye, M.F.,Lavie, A. (登録日: 2010-01-21, 公開日: 2010-03-02, 最終更新日: 2024-02-21)

• 主引用文献: Lye, M.F.,Fanning, A.S.,Su, Y.,Anderson, J.M.,Lavie, A.; Insights into regulated ligand binding sites from the structure of ZO-1 Src homology 3-guanylate kinase module.; J.Biol.Chem., 285:13907-13917, 2010; PubMed: 20200156; DOI: 10.1074/jbc.M109.093674

実験手法

X-RAY DIFFRACTION (2.6 Å)