3LGG
Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2) complexed with transition state analogue, coformycin
Summary for 3LGG
Entry DOI | 10.2210/pdb3lgg/pdb |
Related | 3LGD |
Descriptor | Adenosine deaminase CECR1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (5 entities in total) |
Functional Keywords | tim barrel, dimerization and receptor binding domains, glycoprotein, hydrolase, growth factor, secreted |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: Q9NZK5 |
Total number of polymer chains | 2 |
Total formula weight | 120125.19 |
Authors | Zavialov, A.V. (deposition date: 2010-01-20, release date: 2010-02-09, Last modification date: 2020-07-29) |
Primary citation | Zavialov, A.V.,Yu, X.,Spillmann, D.,Lauvau, G.,Zavialov, A.V. Structural basis for the growth factor activity of human adenosine deaminase ADA2. J.Biol.Chem., 285:12367-12377, 2010 Cited by PubMed: 20147294DOI: 10.1074/jbc.M109.083527 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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