3LGG
Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2) complexed with transition state analogue, coformycin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Adenosine deaminase CECR1 | polymer | 508 | 59049.3 | 2 | UniProt (Q9NZK5) Pfam (PF08451) Pfam (PF00962) In PDB | Homo sapiens (human) | Cat eye syndrome critical region protein 1 |
2 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | A, B | (8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol | non-polymer | 284.3 | 2 | Chemie (CFE) | |||
5 | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 485 (UniProt: Q9NZK5)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Gly 2 | - | expression tag |
Gly 486 | - | expression tag |
Ser 487 | - | expression tag |
Leu 488 | - | expression tag |
His 489 | - | expression tag |
His 490 | - | expression tag |
Ile 491 | - | expression tag |
Leu 492 | - | expression tag |
Asp 493 | - | expression tag |
Ala 494 | - | expression tag |
Gln 495 | - | expression tag |
Lys 496 | - | expression tag |
Met 497 | - | expression tag |
Val 498 | - | expression tag |
Trp 499 | - | expression tag |
Asn 500 | - | expression tag |
His 501 | - | expression tag |
Arg 502 | - | expression tag |
His 503 | - | expression tag |
His 504 | - | expression tag |
His 505 | - | expression tag |
His 506 | - | expression tag |
His 507 | - | expression tag |
His 508 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 118098.6 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 2026.6 | |
All* | Total formula weight | 120125.2 |