3LFM
Crystal structure of the fat mass and obesity associated (FTO) protein reveals basis for its substrate specificity
Summary for 3LFM
Entry DOI | 10.2210/pdb3lfm/pdb |
Descriptor | Protein fto, 3-methylthymidine, N-OXALYLGLYCINE, ... (4 entities in total) |
Functional Keywords | fat mass and obesity associated (fto) protein, fe2+/2-oxoglutarate (2-og)-dependent oxidative dna/rna demethylases, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (By similarity): Q9C0B1 |
Total number of polymer chains | 1 |
Total formula weight | 57282.23 |
Authors | |
Primary citation | Han, Z.,Niu, T.,Chang, J.,Lei, X.,Zhao, M.,Wang, Q.,Cheng, W.,Wang, J.,Feng, Y.,Chai, J. Crystal structure of the FTO protein reveals basis for its substrate specificity Nature, 464:1205-1209, 2010 Cited by PubMed: 20376003DOI: 10.1038/nature08921 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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