3LBX
Crystal Structure of the Erythrocyte Spectrin Tetramerization Domain Complex
Summary for 3LBX
Entry DOI | 10.2210/pdb3lbx/pdb |
Related | 1AJ3 1OWA 2SPC 3EDV 3F31 3KBT |
Descriptor | Spectrin alpha chain, erythrocyte, Spectrin beta chain, erythrocyte (2 entities in total) |
Functional Keywords | spectrin, tetramer, complex, three-helix bundle, alpha helix, partial repeat, helical linker, actin capping, actin-binding, cell shape, cytoskeleton, disease mutation, elliptocytosis, hereditary hemolytic anemia, pyropoikilocytosis, sh3 domain, phosphoprotein, structural protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton: P02549 P11277 |
Total number of polymer chains | 2 |
Total formula weight | 40715.97 |
Authors | Ipsaro, J.J.,Harper, S.L.,Messick, T.E.,Marmorstein, R.,Mondragon, A.,Speicher, D.W. (deposition date: 2010-01-08, release date: 2010-03-09, Last modification date: 2024-02-21) |
Primary citation | Ipsaro, J.J.,Harper, S.L.,Messick, T.E.,Marmorstein, R.,Mondragon, A.,Speicher, D.W. Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex. Blood, 115:4843-4852, 2010 Cited by PubMed: 20197550DOI: 10.1182/blood-2010-01-261396 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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