3L6C
X-ray crystal structure of rat serine racemase in complex with malonate a potent inhibitor
Summary for 3L6C
| Entry DOI | 10.2210/pdb3l6c/pdb |
| Related | 3L6B 3L6R |
| Descriptor | Serine racemase, PYRIDOXAL-5'-PHOSPHATE, MANGANESE (II) ION, ... (5 entities in total) |
| Functional Keywords | pyridoxal phosphate, plp, serine racemase, isomerase |
| Biological source | Rattus norvegicus (rat) |
| Total number of polymer chains | 2 |
| Total formula weight | 73967.66 |
| Authors | Smith, M.A.,Mack, V.,Ebneth, A.,Moraes, I.,Felicetti, B.,Wood, M.,Schonfeld, D.,Mather, O.,Cesura, A.,Barker, J. (deposition date: 2009-12-23, release date: 2010-01-26, Last modification date: 2024-04-03) |
| Primary citation | Smith, M.A.,Mack, V.,Ebneth, A.,Moraes, I.,Felicetti, B.,Wood, M.,Schonfeld, D.,Mather, O.,Cesura, A.,Barker, J. The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. J.Biol.Chem., 285:12873-12881, 2010 Cited by PubMed: 20106978DOI: 10.1074/jbc.M109.050062 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report
