3L5W

Crystal structure of the complex between IL-13 and C836 FAB

Summary for 3L5W

• Entry DOI: 10.2210/pdb3l5w/pdb
• Related: 3L5X 3L5Y
• Descriptor: C836 LIGHT CHAIN, C836 HEAVY CHAIN, Interleukin-13, ... (5 entities in total)
• Functional Keywords: immunoglobulin fold, alpha-helical bundle, cytokine, disulfide bond, glycoprotein, polymorphism, secreted, monoclonal antibody, immune system
• Biological source: Mus musculus, Homo sapiens; More
• Cellular location: Secreted: P35225
• Total number of polymer chains: 6
• Total formula weight: 121641.09

Authors

Teplyakov, A.,Obmolova, G.,Malia, T.,Gilliland, G.L. (deposition date: 2009-12-22, release date: 2010-04-14, Last modification date: 2023-09-06)

• Primary citation: Fransson, J.,Teplyakov, A.,Raghunathan, G.,Chi, E.,Cordier, W.,Dinh, T.,Feng, Y.,Giles-Komar, J.,Gilliland, G.,Lollo, B.,Malia, T.J.,Nishioka, W.,Obmolova, G.,Zhao, S.,Zhao, Y.,Swanson, R.V.,Almagro, J.C.; Human framework adaptation of a mouse anti-human IL-13 antibody.; J.Mol.Biol., 398:214-231, 2010; PubMed: 20226193; DOI: 10.1016/j.jmb.2010.03.004

Experimental method

X-RAY DIFFRACTION (2 Å)