3L3N

Testis ACE co-crystal structure with novel inhibitor lisW

3L3N の概要

• エントリーDOI: 10.2210/pdb3l3n/pdb
• 関連するPDBエントリー: 1o86 1o8a 1uze 1uzf 2iul 3bkk
• 分子名称: Angiotensin-converting enzyme, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total)
• 機能のキーワード: enzyme-inhibitor complex, angiotensin-converting enzyme (ace) inhibitors, testis, carboxypeptidase, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 69482.67

構造登録者

Watermeyer, J.M.,Kroger, W.L.,O'Neil, H.G.,Sewell, B.T.,Sturrock, E.D. (登録日: 2009-12-17, 公開日: 2010-04-28, 最終更新日: 2023-09-06)

• 主引用文献: Watermeyer, J.M.,Kroger, W.L.,O'Neill, H.G.,Sewell, B.T.,Sturrock, E.D.; Characterization of domain-selective inhibitor binding in angiotensin-converting enzyme using a novel derivative of lisinopril.; Biochem.J., 428:67-74, 2010; PubMed: 20233165; DOI: 10.1042/BJ20100056

実験手法

X-RAY DIFFRACTION (2.3 Å)