3L37

PIE12 D-peptide against HIV entry

Summary for 3L37

• Entry DOI: 10.2210/pdb3l37/pdb
• Related: 2R5D 3L34 3L35
• Descriptor: GP41 N-PEPTIDE, HIV ENTRY INHIBITOR PIE12 (3 entities in total)
• Functional Keywords: coiled-coil, d-peptide inhibitor, de novo protein
• Total number of polymer chains: 2
• Total formula weight: 7495.88

Authors

Welch, B.D.,Redman, J.S.,Paul, S.,Whitby, F.G.,Weinstock, M.T.,Reeves, J.D.,Lie, Y.S.,Eckert, D.M.,Hill, C.P.,Root, M.J.,Kay, M.S. (deposition date: 2009-12-16, release date: 2010-11-03, Last modification date: 2011-07-13)

• Primary citation: Welch, B.D.,Francis, J.N.,Redman, J.S.,Paul, S.,Weinstock, M.T.,Reeves, J.D.,Lie, Y.S.,Whitby, F.G.,Eckert, D.M.,Hill, C.P.,Root, M.J.,Kay, M.S.; Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance.; J.Virol., 84:11235-11244, 2010; PubMed: 20719956; DOI: 10.1128/JVI.01339-10

Experimental method

X-RAY DIFFRACTION (1.45 Å)