3L2P

Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching Between Two DNA Bound States

3L2P の概要

• エントリーDOI: 10.2210/pdb3l2p/pdb
• 分子名称: DNA ligase 3, 5'-D(P*CP*GP*GP*GP*AP*TP*GP*CP*GP*TP*C)-3', 5'-D(*GP*TP*CP*GP*GP*AP*CP*TP*G)-3', ... (5 entities in total)
• 機能のキーワード: dna ligase, dna repair, atp-binding, cell cycle, cell division, dna damage, dna recombination, dna replication, ligase, magnesium, metal-binding, nucleotide-binding, nucleus, phosphoprotein, zinc-finger, ligase-dna complex, ligase/dna
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: P49916
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 78874.33

構造登録者

Cotner-Gohara, E.A.,Kim, I.K.,Hammel, M.,Tainer, J.A.,Tomkinson, A.,Ellenberger, T. (登録日: 2009-12-15, 公開日: 2010-07-14, 最終更新日: 2011-07-13)

• 主引用文献: Cotner-Gohara, E.,Kim, I.K.,Hammel, M.,Tainer, J.A.,Tomkinson, A.E.,Ellenberger, T.; Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching between Two DNA-Bound States.; Biochemistry, 49:6165-6176, 2010; PubMed: 20518483; DOI: 10.1021/bi100503w

実験手法

X-RAY DIFFRACTION (3 Å)