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3L28

Crystal structure of Zaire Ebola VP35 interferon inhibitory domain K339A mutant

Summary for 3L28
Entry DOI10.2210/pdb3l28/pdb
Related3FKE 3L25 3L26 3L27 3L29 3L2A
DescriptorPolymerase cofactor VP35, SULFATE ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsrna binding domain, interferon antiviral evasion, rna replication, rna-binding protein, transcription, host cytoplasm, interferon antiviral system evasion, rna-binding, virion, rna binding protein
Biological sourceZaire ebolavirus (ZEBOV)
Cellular locationVirion: Q05127
Total number of polymer chains6
Total formula weight86978.29
Authors
Primary citationLeung, D.W.,Prins, K.C.,Borek, D.M.,Farahbakhsh, M.,Tufariello, J.M.,Ramanan, P.,Nix, J.C.,Helgeson, L.A.,Otwinowski, Z.,Honzatko, R.B.,Basler, C.F.,Amarasinghe, G.K.
Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17:165-172, 2010
Cited by
PubMed: 20081868
DOI: 10.1038/nsmb.1765
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

217705

건을2024-03-27부터공개중

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