3KYM

Crystal structure of Li33 IgG2 di-Fab

Summary for 3KYM

• Entry DOI: 10.2210/pdb3kym/pdb
• Related: 3KYK
• Descriptor: Light Chain Li33 IgG2, Heavy Chain Li33 IgG2 (2 entities in total)
• Functional Keywords: igg2 monoclonal anti-lingo, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 16
• Total formula weight: 383291.56

Authors

Silvian, L.F.,Pepinsky, R.B.,Walus, L. (deposition date: 2009-12-06, release date: 2010-03-16, Last modification date: 2023-09-06)

• Primary citation: Pepinsky, R.B.,Silvian, L.,Berkowitz, S.A.,Farrington, G.,Lugovskoy, A.,Walus, L.,Eldredge, J.,Capili, A.,Mi, S.,Graff, C.,Garber, E.; Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis.; Protein Sci., 19:954-966, 2010; PubMed: 20198683; DOI: 10.1002/pro.372

Experimental method

X-RAY DIFFRACTION (2.62 Å)