3KY9
Autoinhibited Vav1
Summary for 3KY9
Entry DOI | 10.2210/pdb3ky9/pdb |
Descriptor | Proto-oncogene vav, ZINC ION (2 entities in total) |
Functional Keywords | vav1, calponin homology domain, dbl homology domain, pleckstrin homology domain, c1 domain, guanine-nucleotide releasing factor, metal-binding, phosphoprotein, proto-oncogene, sh2 domain, sh3 domain, zinc-finger, apoptosis |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 137668.68 |
Authors | Tomchick, D.R.,Rosen, M.K.,Machius, M.,Yu, B. (deposition date: 2009-12-04, release date: 2010-02-23, Last modification date: 2024-10-16) |
Primary citation | Yu, B.,Martins, I.R.,Li, P.,Amarasinghe, G.K.,Umetani, J.,Fernandez-Zapico, M.E.,Billadeau, D.D.,Machius, M.,Tomchick, D.R.,Rosen, M.K. Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1 Cell(Cambridge,Mass.), 140:246-256, 2010 Cited by PubMed: 20141838DOI: 10.1016/j.cell.2009.12.033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.731 Å) |
Structure validation
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