3KY2
Crystal structure of Fibroblast Growth Factor Receptor 1 kinase domain
Summary for 3KY2
Entry DOI | 10.2210/pdb3ky2/pdb |
Related | 3KXX |
Descriptor | Basic fibroblast growth factor receptor 1, SULFATE ION (3 entities in total) |
Functional Keywords | kinase, rtk, phosphorylation, interface, alternative splicing, atp-binding, chromosomal rearrangement, craniosynostosis, disease mutation, disulfide bond, dwarfism, glycoprotein, heparin-binding, hypogonadotropic hypogonadism, immunoglobulin domain, kallmann syndrome, membrane, nucleotide-binding, phosphoprotein, polymorphism, receptor, transferase, transmembrane, tyrosine-protein kinase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 72837.46 |
Authors | Bae, J.H.,Boggon, T.J.,Tome, F.,Mandiyan, V.,Lax, I.,Schlessinger, J. (deposition date: 2009-12-04, release date: 2010-03-02, Last modification date: 2023-09-06) |
Primary citation | Bae, J.H.,Boggon, T.J.,Tome, F.,Mandiyan, V.,Lax, I.,Schlessinger, J. Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells. Proc.Natl.Acad.Sci.USA, 107:2866-2871, 2010 Cited by PubMed: 20133753DOI: 10.1073/pnas.0914157107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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