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3KVQ

Crystal structure of VEGFR2 extracellular domain D7

Summary for 3KVQ
Entry DOI10.2210/pdb3kvq/pdb
DescriptorVascular endothelial growth factor receptor 2 (2 entities in total)
Functional Keywordsvegfr2, angiogenesis, atp-binding, developmental protein, differentiation, glycoprotein, host-virus interaction, immunoglobulin domain, kinase, membrane, nucleotide-binding, phosphoprotein, polymorphism, receptor, transferase, transmembrane, tyrosine-protein kinase
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein: P35968
Total number of polymer chains1
Total formula weight11912.40
Authors
Yang, Y.,Opatowsky, Y.,Xie, P.,Schlessinger, J. (deposition date: 2009-11-30, release date: 2010-02-16, Last modification date: 2023-09-06)
Primary citationYang, Y.,Xie, P.,Opatowsky, Y.,Schlessinger, J.
Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling
Proc.Natl.Acad.Sci.USA, 107:1906-1911, 2010
Cited by
PubMed: 20080685
DOI: 10.1073/pnas.0914052107
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

217705

건을2024-03-27부터공개중

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