3KV6
Structure of KIAA1718, human Jumonji demethylase, in complex with alpha-ketoglutarate
Summary for 3KV6
Entry DOI | 10.2210/pdb3kv6/pdb |
Related | 3KV4 3KV5 3KV9 3KVA 3KVB |
Descriptor | JmjC domain-containing histone demethylation protein 1D, ZINC ION, FE (II) ION, ... (6 entities in total) |
Functional Keywords | epigenetics, histone code, jumonji lysine demethylase, metal-binding, zinc-finger, h3k4me3 binding protein, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q6ZMT4 |
Total number of polymer chains | 2 |
Total formula weight | 111364.54 |
Authors | Horton, J.R.,Upadhyay, A.K.,Qi, H.H.,Zhang, X.,Shi, Y.,Cheng, X. (deposition date: 2009-11-29, release date: 2009-12-22, Last modification date: 2023-09-06) |
Primary citation | Horton, J.R.,Upadhyay, A.K.,Qi, H.H.,Zhang, X.,Shi, Y.,Cheng, X. Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17:38-43, 2010 Cited by PubMed: 20023638DOI: 10.1038/nsmb.1753 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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