3KTR

Structural basis of ataxin-2 recognition by poly(A)-binding protein

3KTR の概要

• エントリーDOI: 10.2210/pdb3ktr/pdb
• 関連するPDBエントリー: 3KTP
• 分子名称: Polyadenylate-binding protein 1, Ataxin-2, CADMIUM ION, ... (5 entities in total)
• 機能のキーワード: protein-protein complex, acetylation, alternative splicing, cytoplasm, methylation, mrna processing, mrna splicing, nucleus, phosphoprotein, rna-binding, spliceosome, neurodegeneration, parkinsonism, polymorphism, spinocerebellar ataxia, triplet repeat expansion, protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: P11940; Cytoplasm (By similarity): Q99700
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 11665.54

構造登録者

Kozlov, G.,Gehring, K. (登録日: 2009-11-25, 公開日: 2010-02-23, 最終更新日: 2023-09-06)

• 主引用文献: Kozlov, G.,Safaee, N.,Rosenauer, A.,Gehring, K.; Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein.; J.Biol.Chem., 285:13599-13606, 2010; PubMed: 20181956; DOI: 10.1074/jbc.M109.089540

実験手法

X-RAY DIFFRACTION (1.7 Å)