3KSB
Detailed structural insight into the DNA cleavage complex of type IIA topoisomerases (re-sealed form)
Summary for 3KSB
Entry DOI | 10.2210/pdb3ksb/pdb |
Related | 2NOV 3FOE 3FOF 3K9F 3KSA |
Descriptor | DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, 5'-D(*AP*CP*CP*AP*AP*GP*GP*T*CP*AP*TP*GP*AP*AP*TP*GP*AP*CP*TP*AP*TP*GP*CP*AP*CP*GP*TP*AP*AP*AP*AP*CP*AP*G)-3', ... (6 entities in total) |
Functional Keywords | topoisomerase, protein-dna cleavage complex, streptococcus pneumoniae, dna-binding, nucleotide-binding, quinolone, sealed dna form, isomerase-dna complex, isomerase/dna |
Biological source | Streptococcus pneumoniae More |
Cellular location | Cell membrane; Peripheral membrane protein (By similarity): P72525 |
Total number of polymer chains | 6 |
Total formula weight | 194706.39 |
Authors | Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2009-11-21, release date: 2010-05-05, Last modification date: 2023-11-01) |
Primary citation | Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases Plos One, 5:e11338-e11338, 2010 Cited by PubMed: 20596531DOI: 10.1371/journal.pone.0011338 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
Download full validation report