3KSA

Detailed structural insight into the DNA cleavage complex of type IIA topoisomerases (cleaved form)

3KSA の概要

• エントリーDOI: 10.2210/pdb3ksa/pdb
• 関連するPDBエントリー: 2NOV 3FOE 3FOF 3K9F 3KSB
• 分子名称: DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, 5'-D(*AP*CP*CP*AP*AP*GP*GP*T*CP*AP*TP*GP*AP*AP*T)-3', ... (8 entities in total)
• 機能のキーワード: topoisomerase, protein-dna cleavage complex, streptococcus pneumoniae, dna-binding, nucleotide-binding, quinolone, cleaved form, isomerase-dna complex, isomerase/dna
• 由来する生物種: Streptococcus pneumoniae; 詳細
• 細胞内の位置: Cell membrane; Peripheral membrane protein (By similarity): P72525
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 194616.47

構造登録者

Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. (登録日: 2009-11-21, 公開日: 2010-05-05, 最終更新日: 2023-11-01)

• 主引用文献: Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R.; Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases; Plos One, 5:e11338-e11338, 2010; PubMed: 20596531; DOI: 10.1371/journal.pone.0011338

実験手法

X-RAY DIFFRACTION (3.3 Å)