3KLA
Ca2+ release from the endoplasmic reticulum of NY-ESO-1 specific T cells is modulated by the affinity of T cell receptor and by the use of the CD8 co-receptor
3KLA の概要
エントリーDOI | 10.2210/pdb3kla/pdb |
分子名称 | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, NYESO-1 peptide analogue, ... (4 entities in total) |
機能のキーワード | mhc, tumour, immunology, disulfide bond, glycoprotein, immune response, membrane, mhc i, transmembrane, immunoglobulin domain, immune system |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 Cytoplasm: P78358 |
タンパク質・核酸の鎖数 | 6 |
化学式量合計 | 89675.84 |
構造登録者 | Chen, J.L.,Morgan, A.J.,Stewart-Jones, G.,Shepherd, D.,Bossi, G.,Wooldridge, L. (登録日: 2009-11-07, 公開日: 2010-02-16, 最終更新日: 2021-10-13) |
主引用文献 | Chen, J.L.,Morgan, A.J.,Stewart-Jones, G.,Shepherd, D.,Bossi, G.,Wooldridge, L.,Hutchinson, S.L.,Sewell, A.K.,Griffiths, G.M.,van der Merwe, P.A.,Jones, E.Y.,Galione, A.,Cerundolo, V. Ca2+ Release from the Endoplasmic Reticulum of NY-ESO-1-Specific T Cells Is Modulated by the Affinity of TCR and by the Use of the CD8 Coreceptor. J.Immunol., 184:1829-1839, 2010 Cited by PubMed: 20053942DOI: 10.4049/jimmunol.0902103 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.65 Å) |
構造検証レポート
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