3KJR
Crystal structure of dihydrofolate reductase/thymidylate synthase from Babesia bovis determined using SlipChip based microfluidics
Summary for 3KJR
Entry DOI | 10.2210/pdb3kjr/pdb |
Related | 3I3R 3K2H |
Descriptor | Dihydrofolate reductase/thymidylate synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (5 entities in total) |
Functional Keywords | microfluidics, slipchip, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, seattle structural genomics center for infectious disease, methyltransferase, transferase, ssgcid |
Biological source | Babesia bovis T2Bo |
Total number of polymer chains | 2 |
Total formula weight | 118721.88 |
Authors | Li, L.,Du, W.,Edwards, T.E.,Staker, B.L.,Phan, I.,Stacy, R.,Ismagilov, R.F.,Accelerated Technologies Center for Gene to 3D Structure (ATCG3D),Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2009-11-03, release date: 2009-11-17, Last modification date: 2023-09-06) |
Primary citation | Li, L.,Du, W.,Ismagilov, R.F. Multiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods. J.Am.Chem.Soc., 132:112-119, 2010 Cited by PubMed: 20000709DOI: 10.1021/ja908558m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report