3KFX

Human dCK complex with 5-Me dC and ADP

Summary for 3KFX

• Entry DOI: 10.2210/pdb3kfx/pdb
• Descriptor: Deoxycytidine kinase, ADENOSINE-5'-DIPHOSPHATE, 5-METHYL-2'-DEOXYCYTIDINE, ... (4 entities in total)
• Functional Keywords: human dck, nucleotide kinase, p-loop, 5-me dc, atp-binding, kinase, nucleotide-binding, nucleus, phosphoprotein, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P27707
• Total number of polymer chains: 2
• Total formula weight: 66481.91

Authors

Hazra, S.,Lavie, A. (deposition date: 2009-10-28, release date: 2010-09-15, Last modification date: 2024-02-21)

• Primary citation: Hazra, S.,Ort, S.,Konrad, M.,Lavie, A.; Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues .; Biochemistry, 49:6784-6790, 2010; PubMed: 20614893; DOI: 10.1021/bi100839e

Experimental method

X-RAY DIFFRACTION (1.96 Å)