3KEO

Crystal Structure of a Rex-family transcriptional regulatory protein from Streptococcus agalactiae complexed with NAD+

3KEO の概要

• エントリーDOI: 10.2210/pdb3keo/pdb
• 関連するPDBエントリー: 2dt5 2vt3 3KEQ 3KET
• 分子名称: Redox-sensing transcriptional repressor rex, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: dna binding protein, winged helix, rossmann fold, nad+, repressor, transcription, transcription regulation, redox sensing
• 由来する生物種: Streptococcus agalactiae serogroup III
• 細胞内の位置: Cytoplasm : Q8E565
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49233.16

構造登録者

Thiyagarajan, S.,Logan, D.,von Wachenfeldt, C. (登録日: 2009-10-26, 公開日: 2010-11-10, 最終更新日: 2023-11-01)

• 主引用文献: Franza, T.,Rogstam, A.,Thiyagarajan, S.,Sullivan, M.J.,Derre-Bobillot, A.,Bauer, M.C.,Goh, K.G.K.,Da Cunha, V.,Glaser, P.,Logan, D.T.,Ulett, G.C.,von Wachenfeldt, C.,Gaudu, P.; NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence.; Plos Pathog., 17:e1009791-e1009791, 2021; PubMed: 34370789; DOI: 10.1371/journal.ppat.1009791

実験手法

X-RAY DIFFRACTION (1.5 Å)