3KED
Crystal structure of Aminopeptidase N in complex with 2,4-diaminobutyric acid
Summary for 3KED
| Entry DOI | 10.2210/pdb3ked/pdb |
| Related | 2hpo |
| Descriptor | Aminopeptidase N, ZINC ION, 2,4-DIAMINOBUTYRIC ACID, ... (7 entities in total) |
| Functional Keywords | aminopeptidase, thermolysin like active site, amino switch, inhibitor, ligand design, cell inner membrane, cell membrane, hydrolase, membrane, metal-binding, metalloprotease, protease |
| Biological source | Escherichia coli |
| Cellular location | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side: P04825 |
| Total number of polymer chains | 1 |
| Total formula weight | 102811.75 |
| Authors | Addlagatta, A.,Gumpena, R. (deposition date: 2009-10-25, release date: 2010-11-03, Last modification date: 2023-11-01) |
| Primary citation | Gumpena, R.,Kishor, C.,Ganji, R.J.,Addlagatta, A. Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases Chemmedchem, 6:1971-1976, 2011 Cited by PubMed: 22025387DOI: 10.1002/cmdc.201100298 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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