3KDE

Crystal structure of the THAP domain from D. melanogaster P-element transposase in complex with its natural DNA binding site

3KDE の概要

• エントリーDOI: 10.2210/pdb3kde/pdb
• 分子名称: 5'-D(*GP*TP*TP*AP*AP*GP*(BRU)P*GP*GP*A)-3', 5'-D(*(BRU)P*CP*CP*AP*CP*TP*TP*AP*AP*C)-3', Transposable element P transposase, ... (5 entities in total)
• 機能のキーワード: thap domain, dna-binding domain, zinc-finger, beta-alpha-beta, p-element transposase, dna integration, dna recombination, dna-binding, metal-binding, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Drosophila melanogaster (Fruit fly); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 14969.44

構造登録者

Sabogal, A.,Lyubimov, A.Y.,Berger, J.M.,Rio, D.C. (登録日: 2009-10-22, 公開日: 2009-12-08, 最終更新日: 2024-02-21)

• 主引用文献: Sabogal, A.,Lyubimov, A.Y.,Corn, J.E.,Berger, J.M.,Rio, D.C.; THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves.; Nat.Struct.Mol.Biol., 17:117-123, 2010; PubMed: 20010837; DOI: 10.1038/nsmb.1742

実験手法

X-RAY DIFFRACTION (1.74 Å)