3K8D

Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase in complex with CTP and 2-deoxy-Kdo

3K8D の概要

• エントリーDOI: 10.2210/pdb3k8d/pdb
• 関連するPDBエントリー: 3K8E
• 分子名称: 3-deoxy-manno-octulosonate cytidylyltransferase, MAGNESIUM ION, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, ... (5 entities in total)
• 機能のキーワード: kdsb synthetase kdo complex, lipopolysaccharide biosynthesis, magnesium, nucleotidyltransferase, transferase
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm (Potential): P04951
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 120808.12

構造登録者

Heyes, D.J.,Levy, C.W.,Lafite, P.,Scrutton, N.S.,Leys, D. (登録日: 2009-10-14, 公開日: 2009-11-10, 最終更新日: 2023-11-01)

• 主引用文献: Heyes, D.J.,Levy, C.,Lafite, P.,Roberts, I.S.,Goldrick, M.,Stachulski, A.V.,Rossington, S.B.,Stanford, D.,Rigby, S.E.J.,Scrutton, N.S.,Leys, D.; Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases; J.Biol.Chem., 284:35514-35523, 2009; PubMed: 19815542; DOI: 10.1074/jbc.M109.056630

実験手法

X-RAY DIFFRACTION (1.9 Å)