3K8D
Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase in complex with CTP and 2-deoxy-Kdo
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3-deoxy-manno-octulosonate cytidylyltransferase | polymer | 264 | 29456.4 | 4 | UniProt (P04951) Pfam (PF02348) | Escherichia coli | CMP-KDO synthetase, CMP-2-keto-3-deoxyoctulosonic acid synthetase, CKS |
| 2 | E, H, K, N (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 3 | F, I, L, O (A, B, C, D) | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid | non-polymer | 238.2 | 4 | Chemie (KDO) PubChem (445569) PubChem (10082895) PubChem (10243263) PubChem (10354174) PubChem (10857507) PubChem (11736546) PubChem (11776331) PubChem (12775606) PubChem (12775607) PubChem (12775609) PubChem (177608129) PubChem (46936712) PubChem (54120673) PubChem (13990111) PubChem (51351682) PubChem (4636210) PubChem (54120672) PubChem (12775611) PubChem (59879037) PubChem (86308775) PubChem (91130708) PubChem (92131880) PubChem (93477607) PubChem (101259516) PubChem (102104650) PubChem (102502503) PubChem (117731569) PubChem (123948409) PubChem (124526013) PubChem (126544103) PubChem (135037314) PubChem (135040540) PubChem (135041481) PubChem (135070235) PubChem (135081089) PubChem (140373577) PubChem (146415574) PubChem (155539835) PubChem (163811278) PubChem (164803663) PubChem (174067243) | |||
| 4 | G, J, M, P (A, B, C, D) | CYTIDINE-5'-TRIPHOSPHATE | non-polymer | 483.2 | 4 | Chemie (CTP) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 1255 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 248 (UniProt: P04951)
| PDB | External Database | Details |
|---|---|---|
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 117825.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2982.6 | |
| All* | Total formula weight | 120808.1 |
