3K7W

Protein phosphatase 2A core complex bound to dinophysistoxin-2

3K7W の概要

• エントリーDOI: 10.2210/pdb3k7w/pdb
• 関連するPDBエントリー: 2IE4 3K7V
• 分子名称: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: protein-protein complex, heat repeat, signaling protein, phosphatase, ligand specificity, acetylation, polymorphism, centromere, cytoplasm, cytoskeleton, hydrolase, iron, manganese, metal-binding, methylation, nucleus, phosphoprotein, protein phosphatase, signaling protein-hydrolase complex, signaling protein/hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm (By similarity): P30153; Cytoplasm: P67775
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 102217.56

構造登録者

Jeffrey, P.D.,Huhn, J.,Shi, Y. (登録日: 2009-10-13, 公開日: 2009-11-03, 最終更新日: 2023-09-06)

• 主引用文献: Huhn, J.,Jeffrey, P.D.,Larsen, K.,Rundberget, T.,Rise, F.,Cox, N.R.,Arcus, V.,Shi, Y.,Miles, C.O.; A structural basis for the reduced toxicity of dinophysistoxin-2.; Chem.Res.Toxicol., 22:1782-1786, 2009; PubMed: 19916524; DOI: 10.1021/tx9001622

実験手法

X-RAY DIFFRACTION (2.96 Å)